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the fourth object is to select suitable ingredients for transdermal delivery of GHK- Cu to achieve sustained or controlled action

10.1016/j.neuroscience.2015.01.024 39 GeeC

Y.H., Cui J.X., Xia X.J., Mao W.H., Shi K., Asami

Mazurowska, L

Kinetics and persistence research enabled by long acting analogue design Long acting analogues are frequently used in research settings because they can support extended exposure paradigms and persistence studies without requiring constant preparation changes

3 Interactions of autophagy with the cGAS-STING pathway 3.1 cGAS The interplay between autophagy and cGAS occurs through (i) cGAS-Beclin-1 interaction that promotes autophagic degradation of cytosolic dsDNA, (ii) cGAS-LC3 interaction that promotes micronucleophagy, and (iii) degradation of cGAS through p62-mediated selective autophagy ( Figure 3 )